Enhancement of electroporation facilitated immunogene therapy via T-reg depletion

Regulatory T cells (T-regs) can negatively impact tumor antigen-specific immune responses after infiltration into tumor tissue. However, depletion of T-regs can facilitate enhanced anti-tumor responses, thus augmenting the potential for immunotherapies. Here we focus on treating a highly aggressive...

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Autori principali: Forde, P F, Sadadcharam, M, Hall, L J, O' Donovan, T R, de Kruijf, M, Byrne, W L, O' Sullivan, G C, Soden, D M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139741/
https://ncbi.nlm.nih.gov/pubmed/25034887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2014.35
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