Cell-intrinsic lysosomal lipolysis is essential for macrophage alternative activation

Alternative (M2) macrophage activation driven through interleukin 4 receptor α (IL-4Rα) is important for immunity to parasites, wound healing, the prevention of atherosclerosis and metabolic homeostasis. M2 polarization is dependent on fatty acid oxidation (FAO), but the source of fatty acids to sup...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Huang, Stanley Ching-Cheng, Everts, Bart, Ivanova, Yulia, O'Sullivan, David, Nascimento, Marcia, Smith, Amber M., Beatty, Wandy, Love-Gregory, Latisha, Lam, Wing Y., O'Neill, Christina M., Yan, Cong, Du, Hong, Abumrad, Nada A., Urban, Joseph F., Artyomov, Maxim N., Pearce, Erika L., Pearce, Edward J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139419/
https://ncbi.nlm.nih.gov/pubmed/25086775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2956
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