Heavy Metal-induced Metallothionein Expression Is Regulated by Specific Protein Phosphatase 2A Complexes

Induction of metallothionein (MT) expression is involved in metal homeostasis and detoxification. To identify the key pathways that regulate metal-induced cytotoxicity, we investigate how phosphorylated metal-responsive transcription factor-1 (MTF-1) contributed to induction of MT expression. Immort...

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Dades bibliogràfiques
Autors principals: Chen, Liping, Ma, Lu, Bai, Qing, Zhu, Xiaonian, Zhang, Jinmiao, Wei, Qing, Li, Daochuan, Gao, Chen, Li, Jie, Zhang, Zhengbao, Liu, Caixia, He, Zhini, Zeng, Xiaowen, Zhang, Aihua, Qu, Weidong, Zhuang, Zhixiong, Chen, Wen, Xiao, Yongmei
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139248/
https://ncbi.nlm.nih.gov/pubmed/24962574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.548677
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