Heavy Metal-induced Metallothionein Expression Is Regulated by Specific Protein Phosphatase 2A Complexes

Induction of metallothionein (MT) expression is involved in metal homeostasis and detoxification. To identify the key pathways that regulate metal-induced cytotoxicity, we investigate how phosphorylated metal-responsive transcription factor-1 (MTF-1) contributed to induction of MT expression. Immort...

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Bibliographic Details
Main Authors: Chen, Liping, Ma, Lu, Bai, Qing, Zhu, Xiaonian, Zhang, Jinmiao, Wei, Qing, Li, Daochuan, Gao, Chen, Li, Jie, Zhang, Zhengbao, Liu, Caixia, He, Zhini, Zeng, Xiaowen, Zhang, Aihua, Qu, Weidong, Zhuang, Zhixiong, Chen, Wen, Xiao, Yongmei
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139248/
https://ncbi.nlm.nih.gov/pubmed/24962574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.548677
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