Heavy Metal-induced Metallothionein Expression Is Regulated by Specific Protein Phosphatase 2A Complexes

Induction of metallothionein (MT) expression is involved in metal homeostasis and detoxification. To identify the key pathways that regulate metal-induced cytotoxicity, we investigate how phosphorylated metal-responsive transcription factor-1 (MTF-1) contributed to induction of MT expression. Immort...

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Main Authors: Chen, Liping, Ma, Lu, Bai, Qing, Zhu, Xiaonian, Zhang, Jinmiao, Wei, Qing, Li, Daochuan, Gao, Chen, Li, Jie, Zhang, Zhengbao, Liu, Caixia, He, Zhini, Zeng, Xiaowen, Zhang, Aihua, Qu, Weidong, Zhuang, Zhixiong, Chen, Wen, Xiao, Yongmei
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2014
Ábhair:
Cell Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139248/
https://ncbi.nlm.nih.gov/pubmed/24962574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.548677
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