Heavy Metal-induced Metallothionein Expression Is Regulated by Specific Protein Phosphatase 2A Complexes

Induction of metallothionein (MT) expression is involved in metal homeostasis and detoxification. To identify the key pathways that regulate metal-induced cytotoxicity, we investigate how phosphorylated metal-responsive transcription factor-1 (MTF-1) contributed to induction of MT expression. Immort...

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Hlavní autoři: Chen, Liping, Ma, Lu, Bai, Qing, Zhu, Xiaonian, Zhang, Jinmiao, Wei, Qing, Li, Daochuan, Gao, Chen, Li, Jie, Zhang, Zhengbao, Liu, Caixia, He, Zhini, Zeng, Xiaowen, Zhang, Aihua, Qu, Weidong, Zhuang, Zhixiong, Chen, Wen, Xiao, Yongmei
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139248/
https://ncbi.nlm.nih.gov/pubmed/24962574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.548677
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