Heavy Metal-induced Metallothionein Expression Is Regulated by Specific Protein Phosphatase 2A Complexes

Induction of metallothionein (MT) expression is involved in metal homeostasis and detoxification. To identify the key pathways that regulate metal-induced cytotoxicity, we investigate how phosphorylated metal-responsive transcription factor-1 (MTF-1) contributed to induction of MT expression. Immort...

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Detalhes bibliográficos
Main Authors: Chen, Liping, Ma, Lu, Bai, Qing, Zhu, Xiaonian, Zhang, Jinmiao, Wei, Qing, Li, Daochuan, Gao, Chen, Li, Jie, Zhang, Zhengbao, Liu, Caixia, He, Zhini, Zeng, Xiaowen, Zhang, Aihua, Qu, Weidong, Zhuang, Zhixiong, Chen, Wen, Xiao, Yongmei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139248/
https://ncbi.nlm.nih.gov/pubmed/24962574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.548677
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