Differential Regulation of Cyclin D1 Expression by Protein Kinase C α and ϵ Signaling in Intestinal Epithelial Cells

Cellular accumulation of cyclin D1, a key regulator of cell proliferation and tumorigenesis, is subject to tight control. Our previous studies have identified PKCα as a negative regulator of cyclin D1 in the intestinal epithelium. However, treatment of non-transformed IEC-18 ileal crypt cells with P...

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Bibliographische Detailangaben
Hauptverfasser: Pysz, Marybeth A., Hao, Fang, Hizli, A. Asli, Lum, Michelle A., Swetzig, Wendy M., Black, Adrian R., Black, Jennifer D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139238/
https://ncbi.nlm.nih.gov/pubmed/24914206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.571554
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