Protein Kinase Cα Signaling Regulates Inhibitor of DNA Binding 1 in the Intestinal Epithelium

Increasing evidence supports a role for PKCα in growth arrest and tumor suppression in the intestinal epithelium. In contrast, the Id1 transcriptional repressor has pro-proliferative and tumorigenic properties in this tissue. Here, we identify Id1 as a novel target of PKCα signaling. Using a highly...

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Hlavní autoři: Hao, Fang, Pysz, Marybeth A., Curry, Kathryn J., Haas, Kristin N., Seedhouse, Steven J., Black, Adrian R., Black, Jennifer D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093883/
https://ncbi.nlm.nih.gov/pubmed/21454537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.208488
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