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Sin3b Interacts with Myc and Decreases Myc Levels

Myc expression is deregulated in many human cancers. A yeast two-hybrid screen has revealed that the transcriptional repressor Sin3b interacts with Myc protein. Endogenous Myc and Sin3b co-localize and interact in the nuclei of human and rat cells, as assessed by co-immunoprecipitation, immunofluore...

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Detalles Bibliográficos
Main Authors: Garcia-Sanz, Pablo, Quintanilla, Andrea, Lafita, M. Carmen, Moreno-Bueno, Gema, García-Gutierrez, Lucia, Tabor, Vedrana, Varela, Ignacio, Shiio, Yuzuru, Larsson, Lars-Gunnar, Portillo, Francisco, Leon, Javier
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139234/
https://ncbi.nlm.nih.gov/pubmed/24951594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.538744
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