Cdk2: a key regulator of the senescence control function of Myc

Proto-oncogenes such as MYC and RAS promote normal cell growth but fuel tumor development when deregulated. However, over-activated Myc and Ras also trigger intrinsic tumor suppressor mechanisms leading to apoptosis and senescence, respectively. When expressed together MYC and RAS are sufficient for...

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Detaylı Bibliyografya
Asıl Yazarlar: Hydbring, Per, Larsson, Lars-Gunnar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2010
Konular:
Research Perspective
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881513/
https://ncbi.nlm.nih.gov/pubmed/20445224
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