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Different Biochemical Properties Explain Why Two Equivalent Gα Subunit Mutants Cause Unrelated Diseases
There is an increasing number of disease-associated Gα mutations identified from genome-wide sequencing campaigns or targeted efforts. Albright's Hereditary Osteodystrophy (AHO) was the first inherited disease associated with loss-of-function mutations in a G protein (Gαs) and other studies rev...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4139202/ https://ncbi.nlm.nih.gov/pubmed/24982418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.549790 |
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