Evolutionary Conservation of a GPCR-Independent Mechanism of Trimeric G Protein Activation

Trimeric G protein signaling is a fundamental mechanism of cellular communication in eukaryotes. The core of this mechanism consists of activation of G proteins by the guanine-nucleotide exchange factor (GEF) activity of G protein coupled receptors. However, the duration and amplitude of G protein-m...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Coleman, Brantley D., Marivin, Arthur, Parag-Sharma, Kshitij, DiGiacomo, Vincent, Kim, Seongseop, Pepper, Judy S., Casler, Jason, Nguyen, Lien T., Koelle, Michael R., Garcia-Marcos, Mikel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Discoveries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760084/
https://ncbi.nlm.nih.gov/pubmed/26659249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv336
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