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Therapeutic potential of cyclodextrins in the treatment of Niemann–Pick type C disease
Niemann–Pick type C (NPC) disease is an autosomal recessive neurovisceral lipid and storage disorder characterized by abnormal sequestration of unesterified cholesterol within the late endosomal/lysosomal compartment of all cells in the body. This disease primarily affects children and is characteri...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138883/ https://ncbi.nlm.nih.gov/pubmed/25152773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/clp.12.31 |
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