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Computational design of self-assembling protein nanomaterials with atomic level accuracy
We describe a general computational method for designing proteins that self-assemble to a desired symmetric architecture. Protein building blocks are docked together symmetrically to identify complementary packing arrangements, and low-energy protein-protein interfaces are then designed between the...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138882/ https://ncbi.nlm.nih.gov/pubmed/22654060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1219364 |
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