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Near-atomic cryo-EM imaging of a small protein displayed on a designed scaffolding system

Current single-particle cryo-electron microscopy (cryo-EM) techniques can produce images of large protein assemblies and macromolecular complexes at atomic level detail without the need for crystal growth. However, proteins of smaller size, typical of those found throughout the cell, are not present...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Liu, Yuxi, Gonen, Shane, Gonen, Tamir, Yeates, Todd O.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879686/
https://ncbi.nlm.nih.gov/pubmed/29507202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718825115
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