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Structural basis for ebolavirus matrix assembly and budding; protein plasticity allows multiple functions
Proteins, particularly viral proteins, can be multifunctional, but the mechanism(s) behind this trait are not fully understood. Here, we illustrate through multiple crystal structures, biochemistry and cellular microscopy that VP40 rearranges into different structures, each with a distinct function...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138722/ https://ncbi.nlm.nih.gov/pubmed/23953110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.07.015 |
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