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Structural basis for ebolavirus matrix assembly and budding; protein plasticity allows multiple functions

Proteins, particularly viral proteins, can be multifunctional, but the mechanism(s) behind this trait are not fully understood. Here, we illustrate through multiple crystal structures, biochemistry and cellular microscopy that VP40 rearranges into different structures, each with a distinct function...

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Sonraí Bibleagrafaíochta
Main Authors: Bornholdt, Zachary A., Noda, Takeshi, Abelson, Dafna M., Halfmann, Peter, Wood, Malcolm, Kawaoka, Yoshihiro, Saphire, Erica Ollmann
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138722/
https://ncbi.nlm.nih.gov/pubmed/23953110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.07.015
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