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Structural basis for ebolavirus matrix assembly and budding; protein plasticity allows multiple functions

Proteins, particularly viral proteins, can be multifunctional, but the mechanism(s) behind this trait are not fully understood. Here, we illustrate through multiple crystal structures, biochemistry and cellular microscopy that VP40 rearranges into different structures, each with a distinct function...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Bornholdt, Zachary A., Noda, Takeshi, Abelson, Dafna M., Halfmann, Peter, Wood, Malcolm, Kawaoka, Yoshihiro, Saphire, Erica Ollmann
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138722/
https://ncbi.nlm.nih.gov/pubmed/23953110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.07.015
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