Macrophage Metalloelastase (MMP12) Regulates Adipose Tissue Expansion, Insulin Sensitivity, and Expression of Inducible Nitric Oxide Synthase

Macrophage metalloelastase, a matrix metallopeptidase (MMP12) predominantly expressed by mature tissue macrophages, is implicated in pathological processes. However, physiological functions for MMP12 have not been described. Because mRNA levels for the enzyme increase markedly in adipose tissue of o...

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Bibliografski detalji
Glavni autori: Lee, Jung-Ting, Pamir, Nathalie, Liu, Ning-Chun, Kirk, Elizabeth A., Averill, Michelle M., Becker, Lev, Larson, Ilona, Hagman, Derek K., Foster-Schubert, Karen E., van Yserloo, Brian, Bornfeldt, Karin E., LeBoeuf, Renee C., Kratz, Mario, Heinecke, Jay W.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2014
Teme:
Energy Balance-Obesity
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138576/
https://ncbi.nlm.nih.gov/pubmed/24914938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1037
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