Macrophage Metalloelastase (MMP12) Regulates Adipose Tissue Expansion, Insulin Sensitivity, and Expression of Inducible Nitric Oxide Synthase

Macrophage metalloelastase, a matrix metallopeptidase (MMP12) predominantly expressed by mature tissue macrophages, is implicated in pathological processes. However, physiological functions for MMP12 have not been described. Because mRNA levels for the enzyme increase markedly in adipose tissue of o...

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Detalhes bibliográficos
Main Authors: Lee, Jung-Ting, Pamir, Nathalie, Liu, Ning-Chun, Kirk, Elizabeth A., Averill, Michelle M., Becker, Lev, Larson, Ilona, Hagman, Derek K., Foster-Schubert, Karen E., van Yserloo, Brian, Bornfeldt, Karin E., LeBoeuf, Renee C., Kratz, Mario, Heinecke, Jay W.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
Energy Balance-Obesity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138576/
https://ncbi.nlm.nih.gov/pubmed/24914938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1037
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