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The SMRT Coregulator Enhances Growth of Estrogen Receptor-α-Positive Breast Cancer Cells by Promotion of Cell Cycle Progression and Inhibition of Apoptosis

The SMRT coregulator functions as a dual coactivator and corepressor for estrogen receptor-α (ERα) in a gene-specific manner, and in several studies its elevated expression correlates with poor outcome for breast cancer patients. A specific role of SMRT in breast cancer progression has not been eluc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Blackmore, Julia K., Karmakar, Sudipan, Gu, Guowei, Chaubal, Vaishali, Wang, Liguo, Li, Wei, Smith, Carolyn L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138560/
https://ncbi.nlm.nih.gov/pubmed/24971610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1002
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