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Estradiol downregulation of the tumor suppressor gene BTG2 requires estrogen receptor-α and the REA corepressor

B-cell Translocation Gene 2 (BTG2/TIS21/PC3) is an anti-proliferative tumor suppressor gene whose expression is significantly reduced in breast carcinomas, and in MCF-7 and T-47D breast cancer cell lines treated with estradiol (E2). In this study the mechanisms involved in E2 down regulation of BTG2...

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Detalhes bibliográficos
Main Authors: Karmakar, Sudipan, Foster, Estrella A., Smith, Carolyn L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669741/
https://ncbi.nlm.nih.gov/pubmed/19117054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24133
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