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Estradiol downregulation of the tumor suppressor gene BTG2 requires estrogen receptor-α and the REA corepressor
B-cell Translocation Gene 2 (BTG2/TIS21/PC3) is an anti-proliferative tumor suppressor gene whose expression is significantly reduced in breast carcinomas, and in MCF-7 and T-47D breast cancer cell lines treated with estradiol (E2). In this study the mechanisms involved in E2 down regulation of BTG2...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669741/ https://ncbi.nlm.nih.gov/pubmed/19117054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24133 |
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