Dystrophin deregulation is associated with tumor progression in KIT/PDGFRA mutant gastrointestinal stromal tumors

BACKGROUND: Intragenic deletions of the dystrophin-encoding and muscular dystrophy-associated DMD gene have been recently described in gastrointestinal stromal tumor (GIST), rhabdomyosarcoma (RMS) and leiomyosarcoma (LMS). We evaluated the copy numbers and gene expression levels of DMD in our series...

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Hauptverfasser: Pantaleo, Maria A, Astolfi, Annalisa, Urbini, Milena, Fuligni, Fabio, Saponara, Maristella, Nannini, Margherita, Lolli, Cristian, Indio, Valentina, Santini, Donatella, Ercolani, Giorgio, Brandi, Giovanni, Pinna, Antonio D, Biasco, Guido
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Short Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138414/
https://ncbi.nlm.nih.gov/pubmed/25143820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3329-4-9
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