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Dystrophin deregulation is associated with tumor progression in KIT/PDGFRA mutant gastrointestinal stromal tumors

BACKGROUND: Intragenic deletions of the dystrophin-encoding and muscular dystrophy-associated DMD gene have been recently described in gastrointestinal stromal tumor (GIST), rhabdomyosarcoma (RMS) and leiomyosarcoma (LMS). We evaluated the copy numbers and gene expression levels of DMD in our series...

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Detalhes bibliográficos
Main Authors: Pantaleo, Maria A, Astolfi, Annalisa, Urbini, Milena, Fuligni, Fabio, Saponara, Maristella, Nannini, Margherita, Lolli, Cristian, Indio, Valentina, Santini, Donatella, Ercolani, Giorgio, Brandi, Giovanni, Pinna, Antonio D, Biasco, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138414/
https://ncbi.nlm.nih.gov/pubmed/25143820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3329-4-9
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