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Establishment of transgenic lines to monitor and manipulate Yap/Taz-Tead activity in zebrafish reveals both evolutionarily conserved and divergent functions of the Hippo pathway

To investigate the role of Hippo pathway signaling during vertebrate development transgenic zebrafish lines were generated and validated to dynamically monitor and manipulate Yap/Taz-Tead activity. Spatial and temporal analysis of Yap/Taz-Tead activity suggested the importance of Hippo signaling dur...

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Detalhes bibliográficos
Main Authors: Miesfeld, Joel B., Link, Brian A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138299/
https://ncbi.nlm.nih.gov/pubmed/24560909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2014.02.003
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