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Ancestral inference in tumors: how much can we know?
A tumor is thought to start from a single cell and genome. Yet genomes in the final tumor are typically heterogeneous. The mystery of this intratumoral heterogeneity (ITH) has not yet been uncovered, but much of this ITH may be secondary to replication errors. Methylation of cytosine bases often exh...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138290/ https://ncbi.nlm.nih.gov/pubmed/24907673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2014.05.027 |
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