A carregar...

Gaucher iPSC-derived macrophages produce elevated levels of inflammatory mediators and serve as a new platform for therapeutic development

Gaucher disease (GD) is an autosomal recessive disorder caused by mutations in the acid beta-glucocerebrosidase (GBA) gene. The hallmark of GD is the presence of lipid-laden Gaucher macrophages, which infiltrate bone marrow and other organs. These pathological macrophages are believed to be the sour...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Panicker, Leelamma M., Miller, Diana, Awad, Ola, Bose, Vivek, Lun, Yu, Park, Tea Soon, Zambidis, Elias T., Sgambato, Judi A., Feldman, Ricardo A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138241/
https://ncbi.nlm.nih.gov/pubmed/24801745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1732
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!