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A Single Step Approach to Piperidines via Ni-Catalyzed β-Carbon Elimination
[Image: see text] An easy and expeditious route to substituted piperidines is described. A Ni-phosphine complex was used as catalyst for [4 + 2] cycloaddition of 3-azetidinone and alkynes. The reaction has broad substrate scope and affords piperidines in excellent yields and excellent regioselectivi...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138124/ https://ncbi.nlm.nih.gov/pubmed/22468962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol300534j |
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