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A Single Step Approach to Piperidines via Ni-Catalyzed β-Carbon Elimination

[Image: see text] An easy and expeditious route to substituted piperidines is described. A Ni-phosphine complex was used as catalyst for [4 + 2] cycloaddition of 3-azetidinone and alkynes. The reaction has broad substrate scope and affords piperidines in excellent yields and excellent regioselectivi...

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Detalhes bibliográficos
Main Authors: Kumar, Puneet, Louie, Janis
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138124/
https://ncbi.nlm.nih.gov/pubmed/22468962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol300534j
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