Assessment of EGFR Mutations in Circulating Tumor Cell Preparations from NSCLC Patients by Next Generation Sequencing: Toward a Real-Time Liquid Biopsy for Treatment

INTRODUCTION: Assessment of EGFR mutation in non-small cell lung cancer (NSCLC) patients is mandatory for optimization of pharmacologic treatment. In this respect, mutation analysis of circulating tumor cells (CTCs) may be desirable since they may provide real-time information on patient's dise...

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Detalhes bibliográficos
Main Authors: Marchetti, Antonio, Del Grammastro, Maela, Felicioni, Lara, Malatesta, Sara, Filice, Giampaolo, Centi, Irene, De Pas, Tommaso, Santoro, Armando, Chella, Antonio, Brandes, Alba Ariela, Venturino, Paola, Cuccurullo, Franco, Crinò, Lucio, Buttitta, Fiamma
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138040/
https://ncbi.nlm.nih.gov/pubmed/25137181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103883
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