Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment

In Non-Small-Cell Lung Cancer (NSCLC) patients treated with Tyrosine Kinase-Inhibitors (TKIs) therapy, the emergence of acquired resistance can be investigated by plasma monitoring of circulating tumor DNA (ctDNA). A series of 116 patients with EGFR-positive lung adenocarcinomas were treated with fi...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Buttitta, Fiamma, Felicioni, Lara, Lorito, Alessia Di, Cortellini, Alessio, Irtelli, Luciana, Brocco, Davide, Marino, Pietro Di, Traisci, Donatella, D’Ostilio, Nicola, Paolo, Alessandra Di, Malorgio, Francesco, Assalone, Pasquale, Felice, Sonia Di, Fabbri, Francesca, Cianci, Giovanni, Tursi, Michele De, Marchetti, Antonio
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2020
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082112/
https://ncbi.nlm.nih.gov/pubmed/32215186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27517
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