The fish oil ingredient, docosahexaenoic acid, activates cytosolic phospholipase A(2) via GPR120 receptor to produce prostaglandin E(2) and plays an anti-inflammatory role in macrophages

Docosahexaenoic acid (DHA) is one of the major ingredients of fish oil and has been reported to have anti-inflammatory properties mediated through the GPR120 receptor. Whether cytosolic phospholipase A(2) (cPLA(2)) and lipid mediators produced from cPLA(2) activation are involved in the anti-inflamm...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Yueqin, Chen, Li-Yuan, Sokolowska, Milena, Eberlein, Michael, Alsaaty, Sara, Martinez-Anton, Asuncion, Logun, Carolea, Qi, Hai-Yan, Shelhamer, James H
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137958/
https://ncbi.nlm.nih.gov/pubmed/24673159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12296
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