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1α,25-dihydroxyvitamin D3 in combination with transforming growth factor-β increases the frequency of Foxp3(+) regulatory T cells through preferential expansion and usage of interleukin-2

A high prevalence of vitamin D insufficiency and deficiency exists worldwide, which is associated with an increased incidence and severity of a range of immune-mediated diseases. This has resulted in considerable interest in the immunodulatory functions of vitamin D. The active form of vitamin D, 1α...

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Detalhes bibliográficos
Main Authors: Chambers, Emma S, Suwannasaen, Duangchan, Mann, Elizabeth H, Urry, Zoe, Richards, David F, Lertmemongkolchai, Ganjana, Hawrylowicz, Catherine M
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137955/
https://ncbi.nlm.nih.gov/pubmed/24673126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12289
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