1α,25-Dihydroxyvitamin D3 promotes CD200 expression by human peripheral and airway-resident T cells

BACKGROUND: CD200, a cell-surface immunoglobulin-like molecule expressed by immune and stromal cells, dampens the pro-inflammatory activity of tissue-resident innate cells via its receptor, CD200R. This interaction appears critical for peripheral immune tolerance, particularly in the airways where e...

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Hlavní autoři: Dimeloe, Sarah, Richards, David F, Urry, Zoe L, Gupta, Atul, Stratigou, Victoria, Farooque, Sophie, Saglani, Sejal, Bush, Andrew, Hawrylowicz, Catherine M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471129/
https://ncbi.nlm.nih.gov/pubmed/22334534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2011-200651
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