The role of 1α,25-dihydroxyvitamin D3 and cytokines in the promotion of distinct Foxp3(+) and IL-10(+) CD4(+) T cells

1α,25-Dihydroxyvitamin D3 (1α25VitD3) has potent immunomodulatory properties. We have previously demonstrated that 1α25VitD3 promotes human and murine IL-10-secreting CD4(+) T cells. Because of the clinical relevance of this observation, we characterized these cells further and investigated their re...

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Bibliographic Details
Main Authors: Urry, Zoë, Chambers, Emma S., Xystrakis, Emmanuel, Dimeloe, Sarah, Richards, David F., Gabryšová, Leona, Christensen, Jillian, Gupta, Atul, Saglani, Sejal, Bush, Andrew, O’Garra, Anne, Brown, Zarin, Hawrylowicz, Catherine M.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471131/
https://ncbi.nlm.nih.gov/pubmed/22903229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242370
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