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A high-throughput shotgun mutagenesis approach to mapping B-cell antibody epitopes

Characterizing the binding sites of monoclonal antibodies (mAbs) on protein targets, their ‘epitopes’, can aid in the discovery and development of new therapeutics, diagnostics and vaccines. However, the speed of epitope mapping techniques has not kept pace with the increasingly large numbers of mAb...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Davidson, Edgar, Doranz, Benjamin J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137951/
https://ncbi.nlm.nih.gov/pubmed/24854488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12323
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