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A high-throughput shotgun mutagenesis approach to mapping B-cell antibody epitopes
Characterizing the binding sites of monoclonal antibodies (mAbs) on protein targets, their ‘epitopes’, can aid in the discovery and development of new therapeutics, diagnostics and vaccines. However, the speed of epitope mapping techniques has not kept pace with the increasingly large numbers of mAb...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BlackWell Publishing Ltd
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137951/ https://ncbi.nlm.nih.gov/pubmed/24854488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12323 |
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