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A high-throughput shotgun mutagenesis approach to mapping B-cell antibody epitopes
Characterizing the binding sites of monoclonal antibodies (mAbs) on protein targets, their ‘epitopes’, can aid in the discovery and development of new therapeutics, diagnostics and vaccines. However, the speed of epitope mapping techniques has not kept pace with the increasingly large numbers of mAb...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137951/ https://ncbi.nlm.nih.gov/pubmed/24854488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12323 |
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