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A high-throughput shotgun mutagenesis approach to mapping B-cell antibody epitopes

Characterizing the binding sites of monoclonal antibodies (mAbs) on protein targets, their ‘epitopes’, can aid in the discovery and development of new therapeutics, diagnostics and vaccines. However, the speed of epitope mapping techniques has not kept pace with the increasingly large numbers of mAb...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Davidson, Edgar, Doranz, Benjamin J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BlackWell Publishing Ltd 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137951/
https://ncbi.nlm.nih.gov/pubmed/24854488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12323
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