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Virtual screening of integrase inhibitors by large scale binding free energy calculations: the SAMPL4 challenge

As part of the SAMPL4 blind challenge, filtered AutoDock Vina ligand docking predictions and large scale binding energy distribution analysis method binding free energy calculations have been applied to the virtual screening of a focused library of candidate binders to the LEDGF site of the HIV inte...

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Bibliografski detalji
Glavni autori: Gallicchio, Emilio, Deng, Nanjie, He, Peng, Wickstrom, Lauren, Perryman, Alexander L., Santiago, Daniel N., Forli, Stefano, Olson, Arthur J., Levy, Ronald M.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137862/
https://ncbi.nlm.nih.gov/pubmed/24504704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-014-9711-9
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