Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations

AIMS: Citalopram (CT) and escitalopram (S-CT) are among the most widely prescribed selective serotonin reuptake inhibitors used to treat major depressive disorder (MDD). We applied a genome-wide association study to identify genetic factors that contribute to variation in plasma concentrations of CT...

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Autors principals: Ji, Yuan, Schaid, Daniel J, Desta, Zeruesenay, Kubo, Michiaki, Batzler, Anthony J, Snyder, Karen, Mushiroda, Taisei, Kamatani, Naoyuki, Ogburn, Evan, Hall-Flavin, Daniel, Flockhart, David, Nakamura, Yusuke, Mrazek, David A, Weinshilboum, Richard M
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2014
Matèries:
Pharmacogenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137829/
https://ncbi.nlm.nih.gov/pubmed/24528284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12348
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