Glycine and a Glycine Dehydrogenase (GLDC) SNP as Citalopram/Escitalopram Response Biomarkers in Depression: Pharmacometabolomics-informed Pharmacogenomics

Major depressive disorder (MDD) is a common psychiatric disease. Selective serotonin reuptake inhibitors (SSRIs) are an important class of drugs used to treat MDD. However, many patients do not respond adequately to SSRI therapy. We used a pharmacometabolomics-informed pharmacogenomic research strat...

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Hlavní autoři: Ji, Yuan, Hebbring, Scott, Zhu, Hongjie, Jenkins, Gregory D, Biernacka, Joanna, Snyder, Karen, Drews, Maureen, Fiehn, Oliver, Zeng, Zhaobang, Schaid, Daniel, Mrazek, David A., Kaddurah-Daouk, Rima, Weinshilboum, Richard M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034442/
https://ncbi.nlm.nih.gov/pubmed/21107318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2010.250
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