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Using VAAST to Identify Disease-Associated Variants in Next-Generation Sequencing Data

The VAAST pipeline is specifically designed to identify disease-associated alleles in next-generation sequencing data. In the protocols presented in this paper, we outline the best practices for variant prioritization using VAAST. Examples and test data are provided for case-control, small pedigree,...

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Detalhes bibliográficos
Main Authors: Kennedy, Brett, Kronenberg, Zev, Hu, Hao, Moore, Barry, Flygare, Steven, Reese, Martin G., Jorde, Lynn B., Yandell, Mark, Huff, Chad
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137768/
https://ncbi.nlm.nih.gov/pubmed/24763993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142905.hg0614s81
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