Transcription activation by Myc and Max: flanking sequences target activation to a subset of CACGTG motifs in vivo.

The Myc oncoprotein has been implicated in control of cell growth, division and differentiation. Although Myc contains a bHLH-LZ motif, it fails to bind DNA alone but can do so by forming heterodimers with an unrelated bHLH-LZ protein, Max. Max homodimers and Myc-Max heterodimers share the ability t...

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Enregistré dans:
Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Fisher, F, Crouch, D H, Jayaraman, P S, Clark, W, Gillespie, D A, Goding, C R
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1993
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413768/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8262050/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06201.x
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