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Transcription activation by Myc and Max: flanking sequences target activation to a subset of CACGTG motifs in vivo.

The Myc oncoprotein has been implicated in control of cell growth, division and differentiation. Although Myc contains a bHLH-LZ motif, it fails to bind DNA alone but can do so by forming heterodimers with an unrelated bHLH-LZ protein, Max. Max homodimers and Myc-Max heterodimers share the ability t...

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Autores principales: Fisher, F, Crouch, D H, Jayaraman, P S, Clark, W, Gillespie, D A, Goding, C R
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC413768/
https://ncbi.nlm.nih.gov/pubmed/8262050
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