The patterns of binding of RAR, RXR and TR homo- and heterodimers to direct repeats are dictated by the binding specificites of the DNA binding domains.

We show here that, in addition to generating an increase in DNA binding efficiency, heterodimerization of retinoid X receptor (RXR) with either retinoic acid receptor (RAR) or thyroid hormone receptor (TR) alters the binding site repertoires of RAR, RXR and TR homodimers. The binding site specificit...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Mader, S, Chen, J Y, Chen, Z, White, J, Chambon, P, Gronemeyer, H
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1993
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC413763/
https://ncbi.nlm.nih.gov/pubmed/8262045
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