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dUTP pyrophosphatase is an essential enzyme in Saccharomyces cerevisiae.

dUTP pyrophosphatase (dUTPase; EC 3.6.1.23) catalyses the hydrolysis of dUTP to dUMP and PPi and thereby prevents the incorporation of uracil into DNA during replication. Although it is widely believed that dUTPase is essential for cell viability because of this role, direct evidence supporting this...

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書目詳細資料
發表在:EMBO J
Principais autores: Gadsden, M H, McIntosh, E M, Game, J C, Wilson, P J, Haynes, R H
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 1993
主題:
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413740/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8223452/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06127.x
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