Developmental and functional impairment of T cells in mice lacking CD3 zeta chains.

CD3 zeta is a component of the T cell antigen receptor (TCR) complex and is important for signal transduction. We have established mice selectively lacking CD3 zeta but able to express CD3 eta, a polypeptide produced from the same locus through alternative splicing, using the method of gene targetin...

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Hlavní autoři: Ohno, H, Aoe, T, Taki, S, Kitamura, D, Ishida, Y, Rajewsky, K, Saito, T
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC413732/
https://ncbi.nlm.nih.gov/pubmed/8223445
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