Developmental and functional impairment of T cells in mice lacking CD3 zeta chains.

CD3 zeta is a component of the T cell antigen receptor (TCR) complex and is important for signal transduction. We have established mice selectively lacking CD3 zeta but able to express CD3 eta, a polypeptide produced from the same locus through alternative splicing, using the method of gene targetin...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Ohno, H, Aoe, T, Taki, S, Kitamura, D, Ishida, Y, Rajewsky, K, Saito, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413732/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8223445/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06120.x
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