Targeted disruption of the CD3 eta locus causes high lethality in mice: modulation of Oct-1 transcription on the opposite strand.

CD3 zeta and eta chains are components of the T cell antigen receptor (TCR) complex and are transcribed from a common gene by alternative splicing. TCR complexes containing the zeta eta dimer have been thought to mediate different functions than complexes containing the zeta 2 dimer. To analyze the...

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Bibliographic Details
Published in:EMBO J
Main Authors: Ohno, H, Goto, S, Taki, S, Shirasawa, T, Nakano, H, Miyatake, S, Aoe, T, Ishida, Y, Maeda, H, Shirai, T
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394925/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8131747/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06365.x
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