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IPF1, a homeodomain-containing transactivator of the insulin gene.

We describe the cloning of insulin promoter factor 1 (IPF1), a homeodomain protein which in the adult mouse pancreas is selectively expressed in the beta-cells and which binds to and transactivates the insulin promoter. In embryos, IPF1 expression is initiated prior to hormone gene expression and is...

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Publicat a:EMBO J
Autors principals: Ohlsson, H, Karlsson, K, Edlund, T
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413720/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7901001/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06109.x
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