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IPF1, a homeodomain-containing transactivator of the insulin gene.

We describe the cloning of insulin promoter factor 1 (IPF1), a homeodomain protein which in the adult mouse pancreas is selectively expressed in the beta-cells and which binds to and transactivates the insulin promoter. In embryos, IPF1 expression is initiated prior to hormone gene expression and is...

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Bibliografiske detaljer
Main Authors: Ohlsson, H, Karlsson, K, Edlund, T
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC413720/
https://ncbi.nlm.nih.gov/pubmed/7901001
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