Paired-Homeodomain Transcription Factor PAX4 Acts as a Transcriptional Repressor in Early Pancreatic Development

The paired-homeodomain transcription factor PAX4 is expressed in the developing pancreas and along with PAX6 is required for normal development of the endocrine cells. In the absence of PAX4, the numbers of insulin-producing β cells and somatostatin-producing δ cells are drastically reduced, while t...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Smith, Stuart B., Ee, Hooi C., Conners, Jennifer R., German, Michael S.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 1999
Assuntos:	Transcriptional Regulation
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84911/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10567552/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.12.8272
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